Cancer Therapy: Preclinical Toll-Like Receptor Triggering and T-Cell Costimulation Induce Potent Antitumor Immunity in Mice
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چکیده
Purpose: To determine the antitumor activity of a novel combination of two immunomodAuth MacC and Labo Unive Rece 12/8/0 Gran tralia Canc lum C by a S Natio by a The c page in ac Note Rese P.K. D Requ Progr Victo mich
منابع مشابه
Toll-Like Receptor Triggering and T-Cell Costimulation Induce Potent Antitumor Immunity in Mice.
PURPOSE: To determine the antitumor activity of a novel combination of two immunomodulatory agents that simultaneously direct multiple components of immunity against cancer. EXPERIMENTAL DESIGN: We combined the Toll-like receptor agonist CpG 1826 with a T-cell costimulatory antibody specific for CD137 in an optimal treatment route and dosing schedule against established tumors in two mouse mode...
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